Isolating nerve cell precursors from dental pulp stem cells
2024
Queens University Belfast, Belfast, United Kingdom
Dental pulp stem cells (DPSCs) contain a diverse mix of stem cells with various potential uses, but this diversity can be challenging for research and clinical applications. This study aimed to isolate and study a specific type of nerve cell precursor from human DPSCs. The researchers used a specialized sorting technique to isolate these precursor cells from dental pulp samples from three human donors. They then examined the cells' characteristics and ability to develop into mature nerve cells. The isolated cells showed features of early-stage nerve cells and could be further developed into more mature nerve cells in laboratory conditions. These cells demonstrated functional properties similar to nerve cells, such as responding to certain chemicals and showing electrical activity. Overall, this study shows that dental pulp contains nerve cell precursors that can be effectively isolated and potentially used for further research or medical applications.
Immunological isolation and characterization of neuronal progenitors from human dental pulp: A laboratory-based investigation
Ikhlas El Karim
Added on: 12-20-2024
[1] https://onlinelibrary.wiley.com/doi/10.1111/iej.14077
